Last updated: September 2025
Clinical trials are the pathway to better treatments. For borderline ovarian tumors, where treatment options are still being refined and standardized care approaches continue to evolve, participating in research studies can provide access to innovative approaches and contribute to advancing care for future patients.
Clinical Trials for Borderline Ovarian Tumors
🔬 Registry Studies
These studies collect data to better understand BOT patterns and outcomes:
KOrean Borderline Ovarian Tumor (KOBOT) Registry
- Location: Multiple hospitals across South Korea
What it is: Long-term data collection on Korean BOT patients to improve understanding of diagnosis, treatment, and outcomes - Who can participate: Women diagnosed with borderline ovarian tumors
- Duration: Ongoing through 2040 (started 1994)
- Sponsor: Kangbuk Samsung Hospital
- Why it matters: Helps researchers understand borderline ovarian tumor prognosis and treatment patterns across different populations
- Study ID: NCT02803970
- Status: Last updated April 2019
🧬 Diagnostic Innovation Studies
Salivary RNA Detection Study (OVAmiARN)
- Location: 12 hospitals across France
- What it is: Testing saliva samples to improve ovarian cancer diagnosis
- Who can participate: Women 18+ with suspected ovarian masses requiring surgery
- Duration: Through 2026
- Why it matters: Could lead to earlier, less invasive detection methods
- Study ID: NCT05514028
- Contact: Multiple French medical centers
📱 Follow-up Care Studies
Remote Monitoring vs. In-Person Care (SUR-CAN)
- Location: France (3 centers)
- What it is: Comparing nurse-led remote follow-up to traditional doctor visits
- Who can participate: Adult patients with rare tumors, including borderline ovarian tumors
- Duration: 5-year follow-up
- Why it matters: Could improve ovarian cancer support accessibility
- Study ID: NCT05500391
How to Find Clinical Trials
🔍 Search Resources
- ClinicalTrials.gov: Official U.S. database of clinical studies
- Cancer.gov Clinical Trials Search: NCI’s patient-friendly search tool
- Your gynecologic oncologist: Often has access to institutional trials
📋 Questions to Ask Your Doctor
When discussing clinical trials, consider asking:
- What are the potential benefits and risks?
- How does this compare to standard treatment?
- What follow-up care is required?
- Will my insurance cover trial-related costs?
Understanding Trial Phases
- Observational Studies: Like registries, these collect information without testing treatments
- Phase I: Test safety of new treatments in small groups
- Phase II: Evaluate effectiveness while monitoring safety
- Phase III: Compare new treatments to current standard care
What to Expect
Before Joining
- Detailed informed consent process
- Review of your medical history
- Physical exams and tests
- Discussion of time commitment
During Participation
- Regular study visits
- Careful monitoring of your health
- Access to study team for questions
- Detailed record-keeping
Financial Considerations
Many clinical trials cover:
- Study-related medical care
- Research tests and procedures
- Study medications (if applicable)
You’re typically responsible for:
- Travel costs (some studies provide assistance)
- Regular medical care unrelated to the study
- Personal expenses
Special Considerations for Younger Women
Since borderline ovarian tumors often affect younger women, many trials consider:
- Fertility preservation options
- Long-term quality of life impacts
- Work and family considerations
Stay Updated: Borderline Ovarian Tumors Clinical Trials
New trials open regularly. Bookmark this page and check back for updates, or sign up for our newsletter to stay informed about research developments.